Molecular and Synthetic Biology

Molecular and Synthetic biology

An arsenal of tools to accurately and efficiently modify the molecular workings of cells to gain advantages.

  • Applied Biosystems Proflex PCR system
  • Invitrogen™iBright™ CL1000 Imaging System
  • EVOS™ XL Core Imaging System
  • EVOS™ XL Core Imaging System
  • BEL UV-VIS spectrophotometer UV-M51

OUR TRACK RECORD

  • Technology transfer ( scale down <-> scale up ):
    > 2 lts <-> 200 lts <-> 3000 lts <-> 50000 lts
  • Strain development (Molecular and Synthetic biology; Metabolic Engineering)
    > Development of protocols and methodologies for genetic manipulations of Streptomyces spp (non GMO, GMO), E.coli, Yiests;
    > Mutation and overexpression of genes involved in the biosynthesis of metabolites and/or precursors through knocking-out and/or knocking-in;
    > Identification of regulatory networks and/or molecular pathways involved in the biosynthesis of metabolites and/or precursors by ‘omics’ technologies;
    > Metabolic Engineering;
    > Synthetic biology: targeted amplification, DNA synthesis.